Posted by : Unknown Friday 19 September 2014

Drug metabolism also noted as xenobiotic metabolism is the biochemical alteration of pharmaceutical substances or xenobiotics respectively by living organisms, usually through advanced enzymatic systems. Drug metabolism often convertslipophilic chemical compounds into more readilyexcretedhydrophilic items. The rate of metabolism determines the duration and intensity of a drug's pharmacological action.

Established in 1972, drug metabolism reviews is an academic journal that publishes review articles on all facets of drug metabolism investigation. It is the official journal of the International Society for the Study of Xenobiotics

Current Drug Metabolism works towards to cover all the fresh and outstanding evolutions in drug metabolism and disposition. This journal provides as an international forum for the publication of timely reviews and guest edited issues in drug metabolism. Recent Drug Metabolism is a crucialjournal for academic, clinical, management and medicinal scientists who wish to be kept knowledgeable andupdated with the new and most exclusivecreating. The periodical envelops the following areas:

In vitro systems involving CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and inter individual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation, recent developments for the identification of drug metabolites, adducts and preclinical and clinical summaries of marketed drugs

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